Responsibilities

Employee Relations & HR Support

Serve as a trusted point of contact for employees and managers regarding HR-related questions, including compensation, benefits, PTO, policies, and procedures
Investigate employee relations issues and workplace complaints, recommend corrective actions, and partner with the Legal department and HR leadership as appropriate.
Handle confidential and sensitive employee information with professionalism, discretion, and strict adherence to company privacy and confidentiality standards.
Work closely with managers and employees to strengthen working relationships, enhance engagement, and support employee retention initiatives.

HR Operations & Compliance

Maintain accurate and timely employee data by processing and documenting personnel actions such as new hires, promotions, transfers, job changes, and terminations.
Ensure data integrity across HR systems to support payroll, benefits administration, compliance, and reporting requirements.
Apply working knowledge of employment laws and regulations, including FMLA, ADA, leaves of absence, return-to-work programs, and NLRA; escalate and partner with Legal or HR leadership as needed.
Support audits and ensure compliance with internal policies and external regulatory requirements.

Talent & Employee Lifecycle Support

Assist with new hire onboarding and orientation, including coordination of paperwork, scheduling, and delivery of orientation content.
Support performance management processes, recognition programs, training initiatives, and company-wide HR events.
Assist with benefits administration activities, including open enrollment support, employee education, and issue resolution.

Collaboration & Continuous Improvement

Partner with HR leadership, including the SVP, HR, to support the execution of People initiatives aligned with business objectives.
Act as a liaison with other HR functions to ensure consistent and effective service delivery.
Contribute to HR projects, data analysis, reporting, and process improvements to enhance employee experience and operational efficiency.

Required Skills & Competencies

Working knowledge of compensation practices and benefits administration with the ability to identify issues and apply established programs.
Strong analytical and problem-solving skills, including basic data analysis and interpretation.
Excellent verbal and written communication skills with strong organizational, documentation, and follow-up abilities.
High level of discretion and professionalism when handling confidential and sensitive employee matters.
Proficiency in Microsoft Office applications (Outlook, Word, Excel) and HRIS platforms.
Ability to manage multiple priorities, meet deadlines, and adapt to changing business needs.
Self-motivated, proactive, and collaborative team player.
Ability to interact effectively and professionally with employees at all levels, including management, vendors, and external partners.

Qualifications

Bachelor’s degree in Human Resources, Business Administration, or a related field, or equivalent professional experience.
Minimum of 5–7 years of progressive HR experience, preferably in an HR Generalist or similar role.
Hands-on experience supporting employee relations, HR operations, and compliance.
Familiarity with HR systems, reporting tools, and standard HR processes.
Demonstrated ability to resolve employee issues using sound judgment and practical HR solutions.
Strong organizational skills with attention to detail and accuracy.

The base pay range for this position at commencement of employment is expected to be between $145K and $160K / year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.

Protagonist Therapeutics is a discovery through late-stage development biopharmaceutical company. Two novel peptides, icotrokinra and rusfertide, derived from Protagonist's proprietary discovery platform are currently in advanced Phase 3 clinical development, with New Drug Application submissions to the FDA expected in 2025. Icotrokinra (JNJ-2113) is a first-in-class investigational targeted oral peptide that selectively blocks the Interleukin-23 receptor ("IL-23R") which is licensed to Janssen Biotech, Inc., a Johnson & Johnson company. Following icotrokinra's joint discovery by Protagonist and Johnson & Johnson scientists pursuant to the companies' IL-23R collaboration, Protagonist was primarily responsible for development of icotrokinra through Phase 1, with Johnson & Johnson assuming responsibility for development in Phase 2 and beyond. Rusfertide, a mimetic of the natural hormone hepcidin, is currently in Phase 3 development for the rare blood disorder polycythemia vera (PV). Rusfertide is being co-developed and will be co-commercialized with Takeda Pharmaceuticals pursuant to a worldwide collaboration and license agreement entered into in 2024 under which the Company remains primarily responsible for development through NDA filing. The Company also has a number of pre-clinical stage oral drug discovery programs addressing clinically and commercially validated targets, including the IL-17 oral peptide antagonist PN-881, an oral hepcidin program, and an oral obesity program.

Protagonist Therapeutics

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